Estimating cutoff values for diagnostic tests to achieve target specificity using extreme value theory
Abstract Background Rapidly developing tests for emerging diseases is critical for early disease monitoring. In the early stages of an epidemic, when low prevalences are expected, high specificity tests are desired to avoid numerous false positives. Selecting a cutoff to classify positive and negati...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-02-01
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Series: | BMC Medical Research Methodology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12874-023-02139-5 |