In silico sgRNA tool design for CRISPR control of quorum sensing in Acinetobacter species

In silico sgRNA tool design for CRISPR control of quorum sensing in Acinetobacter species

CRISPR genome editing utilizes Cas9 nuclease and single guide RNA (sgRNA), which directs the nuclease to a specific site in the genome and makes a double-stranded break (DSB). Design of sgRNA for CRISPR-Cas targeting, and to promote CRISPR adaptation, uses a regulatory mechanism that ensures maximum...

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Bibliographic Details
Main Authors: Abraham Peele Karlapudi, Venkateswarulu T.C, Jahnavi Tammineedi, Krupanidhi Srirama, Lohit Kanumuri, Vidya Prabhakar Kodali
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2018-06-01
Series:Genes and Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304218300564

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http://www.sciencedirect.com/science/article/pii/S2352304218300564

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