Lipoxins A4 and B4 inhibit glial cell activation via CXCR3 signaling in acute retinal neuroinflammation

Abstract Lipoxins are small lipids that are potent endogenous mediators of systemic inflammation resolution in a variety of diseases. We previously reported that Lipoxins A4 and B4 (LXA4 and LXB4) have protective activities against neurodegenerative injury. Yet, lipoxin activities and downstream sig...

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Bibliographic Details
Main Authors: Izhar Livne-Bar, Shubham Maurya, Karsten Gronert, Jeremy M. Sivak
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:https://doi.org/10.1186/s12974-024-03010-0