Elucidation of the interaction of apocarotenoids with calf thymus DNA by biophysical techniques and in vitro study in MCF-7 cells to explore their potential in cancer therapy

Objective(s): DNA is one of the targets of cancer-therapeutic small molecules. Cisplatin, a DNA intercalator, is one of the first-line drugs in the cancer chemo regimen which comes with health-compromising side effects during chemotherapy. The synergistic effect of natural molecules with cisplatin c...

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Bibliographic Details
Main Authors: Jill Mathew, Siva Ramamoorthy
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2023-09-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:https://ijbms.mums.ac.ir/article_22476_f56d4c7fd7d1b41c4e2db3bd5f7caa36.pdf