Association between cytomegalovirus infection, reduced gray matter volume, and resting-state functional hypoconnectivity in major depressive disorder: a replication and extension

Abstract Human cytomegalovirus (HCMV) is a neurotropic herpes virus known to cause neuropathology in patients with impaired immunity. Previously, we reported a reduction in the gray matter volume (GMV) of several brain regions in two independent samples of participants who were seropositive for HCMV...

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Bibliographic Details
Main Authors: Haixia Zheng, Bart N. Ford, Rayus Kuplicki, Kaiping Burrows, Peter W. Hunt, Jerzy Bodurka, T. Kent Teague, Michael R. Irwin, Robert H. Yolken, Martin P. Paulus, Jonathan Savitz
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01558-6