Molecular differences between young and mature stria vascularis from organotypic explants and transcriptomics

Summary: The stria vascularis (SV) is an essential component of the inner ear that regulates the ionic environment required for hearing. SV degeneration disrupts cochlear homeostasis, leading to irreversible hearing loss, yet a comprehensive understanding of the SV, and consequently therapeutic avai...

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Bibliographic Details
Main Authors: Matsya Ruppari Thulasiram, Ryosuke Yamamoto, Rafal T. Olszewski, Shoujun Gu, Robert J. Morell, Michael Hoa, Alain Dabdoub
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225000926