Higher levels of plasma Adrenocorticotropic hormone (ACTH) are associated with lower suicidal ideation in depressed patients compared to controls and suicide attempters, independently from depression severity

Higher levels of plasma Adrenocorticotropic hormone (ACTH) are associated with lower suicidal ideation in depressed patients compared to controls and suicide attempters, independently from depression severity

Introduction: Suicidal ideation, an important risk factor for suicide attempts, has an unclear neurobiological basis and is potentially linked to the dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis and immune-inflammatory systems. While inflammatory markers have been associated with s...

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Bibliographic Details
Main Authors: Robertas Strumila, Aiste Lengvenyte, Linas Zdanavicius, Robertas Badaras, Edgaras Dlugauskas, Sigita Lesinskiene, Eimantas Matiekus, Martynas Marcinkevicius, Lina Venceviciene, Algirdas Utkus, Andrius Kaminskas, Tomas Petrenas, Jurgita Songailiene, Dalius Vitkus, Laima Ambrozaityte
Format: Article
Language:English
Published: Elsevier 2024-08-01
Series:Comprehensive Psychoneuroendocrinology
Subjects:
Suicidal ideation
Adrenocorticotropic hormone (ACTH)
Hypothalamic-pituitary-adrenal (HPA) axis
Cortisol
Antidepressants
Major depressive disorder (MDD)
Online Access:http://www.sciencedirect.com/science/article/pii/S2666497624000110

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http://www.sciencedirect.com/science/article/pii/S2666497624000110

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