Integrating Immunologic Signaling Networks: The JAK/STAT Pathway in Colitis and Colitis-Associated Cancer
Cytokines are believed to be crucial mediators of chronic intestinal inflammation in inflammatory bowel diseases (IBD) such as Crohn’s disease (CD) and ulcerative colitis (UC). Many of these cytokines trigger cellular effects and functions through signaling via janus kinase (JAK) and signal transduc...
Main Authors: | Sebastian Zundler, Markus F. Neurath |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-02-01
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Series: | Vaccines |
Subjects: | |
Online Access: | http://www.mdpi.com/2076-393X/4/1/5 |
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