Evidence of Nrf2/Keap1 Signaling Regulation by Mitochodria-Generated Reactive Oxygen Species in RGK1 Cells

It has been known that reactive oxygen species (ROS) are generated from the mitochondrial electron transport chain (ETC). Majima et al. proved that mitochondrial ROS (mtROS) caused apoptosis for the first time in 1998 (Majima et al. J Biol Chem, 1998). It is speculated that mtROS can move out of the...

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Main Authors: Hiroko P. Indo, Daisuke Masuda, Sompong Sriburee, Hiromu Ito, Ikuo Nakanishi, Ken-ichiro Matsumoto, Samlee Mankhetkorn, Moragot Chatatikun, Sirirat Surinkaew, Lunla Udomwech, Fumitaka Kawakami, Takafumi Ichikawa, Hirofumi Matsui, Jitbanjong Tangpong, Hideyuki J. Majima
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Biomolecules
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Online Access:https://www.mdpi.com/2218-273X/13/3/445