Interplay between HGAL and Grb2 proteins regulates B-cell receptor signaling

Abstract: Human germinal center (GC)–associated lymphoma (HGAL) is an adaptor protein expressed in GC B cells. HGAL regulates cell motility and B-cell receptor (BCR) signaling, processes that are central for the successful completion of the GC reaction. Herein, we demonstrate phosphorylation of HGAL...

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Bibliographic Details
Main Authors: Xiaoyu Jiang, Xiaoqing Lu, Yu Zhang, Leda Lacaria, Brett J. Schuchardt, David C. Mikles, Marco Magistri, Idoia García-Ramírez, Isidro Sanchez-Garcia, Amjad Farooq, Ramiro E. Verdun, Midhat H. Abdulreda, Vincent T. Moy, Izidore S. Lossos
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952920306236