Sirt3 in POMC neurons controls energy balance in a sex- and diet-dependent manner

Sirt3 in POMC neurons controls energy balance in a sex- and diet-dependent manner

Sirtuin 3 (SIRT3) is one of the seven mammalian sirtuin homologs of the yeast Sir2 gene that has emerged as an important player in the regulation of energy metabolism in peripheral tissues. However, its role in the hypothalamus has not been explored. Herein, we show that the genetic inhibition of SI...

Full description

Bibliographic Details
Main Authors: Mar Quiñones, René Hernández-Bautista, Daniel Beiroa, Violeta Heras, Francisco L. Torres-Leal, Brian Y.H. Lam, Ana Senra, Johan Fernø, Alicia García Gómez-Valadés, Markus Schwaninger, Vincent Prevot, Giles Yeo, Marc Claret, Miguel López, Carlos Diéguez, Omar Al-Massadi, Ruben Nogueiras
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Redox Biology
Subjects:
Sirtuins
Hypothalamus
brown adipose tissue
Energy balance
Adiposity
Browning
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721000938

Internet

http://www.sciencedirect.com/science/article/pii/S2213231721000938

Similar Items