Environmental and Nutritional “Stressors” and Oligodendrocyte Dysfunction: Role of Mitochondrial and Endoplasmatic Reticulum Impairment

Environmental and Nutritional “Stressors” and Oligodendrocyte Dysfunction: Role of Mitochondrial and Endoplasmatic Reticulum Impairment

Oligodendrocytes are myelinating cells of the central nervous system which are generated by progenitor oligodendrocytes as a result of maturation processes. The main function of mature oligodendrocytes is to produce myelin, a lipid-rich multi-lamellar membrane that wraps tightly around neuronal axon...

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Bibliographic Details
Main Authors: Jessica Maiuolo, Micaela Gliozzi, Vincenzo Musolino, Cristina Carresi, Saverio Nucera, Miriam Scicchitano, Federica Scarano, Francesca Bosco, Francesca Oppedisano, Roberta Macrì, Vincenzo Mollace
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Biomedicines
Subjects:
oligodendrocytes
myelination
oxygen reactive species
endoplasmic reticulum
unfolded protein response
heavy metals
Online Access:https://www.mdpi.com/2227-9059/8/12/553

Internet

https://www.mdpi.com/2227-9059/8/12/553

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