Comparative study of the biological properties of influenza А virus mutants obtained by site-specific mutagenesis and the live influenza reassortant vaccine variant

Comparative study of the biological properties of influenza А virus mutants obtained by site-specific mutagenesis and the live influenza reassortant vaccine variant

The aim of study was to carry out comparative investigation of biological properties of site-specific mutants of Influenza A virus and variant of live cold-adapted (CA) influenza reassortant vaccine. Materials and methods. The genetic stability of site-specific mutants (SSM) of the A/WSN/33 (H1N1...

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Bibliographic Details
Main Authors: Bogdan S. Cherepovich, Artem A. Rtishchev, Irina I. Akopova, Olga V. Borisova, Vladimir Y. Kost, Nina M. Kutuzova, Stanislav G. Markushin
Format: Article
Language:Russian
Published: Central Research Institute for Epidemiology 2022-12-01
Series:Журнал микробиологии, эпидемиологии и иммунобиологии
Subjects:
site-specific mutants
influenza virus
genetic stability
immunogenicity
ca-reassortant
interferonogenicity
live influenza vaccines
Online Access:https://microbiol.crie.ru/jour/article/viewFile/1165/775

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https://microbiol.crie.ru/jour/article/viewFile/1165/775

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