Clearing soluble MIC reverses the impaired function of natural killer cells from patients with multiple myeloma

Background Major histocompatibility complex (MHC) class I chain-related protein (MIC) is a stress-induced ligand released from multiple myeloma (MM) cells during progression, and soluble MIC impairs natural killer group 2D (NKG2D) activating receptor-mediated recognition and function of natural kill...

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Bibliographic Details
Main Authors: Jennifer Wu, June-Won Cheong, Eui-Cheol Shin, Yu Ri Kim, Hyunsoo Cho, Yeonhee Kim, Sojeong Kim, Haerim Chung, Jeong-Eun Kwak, Chung Hyun Park, Jin Seok Kim
Format: Article
Language:English
Published: BMJ Publishing Group 2024-01-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/12/1/e007886.full