Counteracting poisoning with chemical warfare nerve agents
Phosphylation of the pivotal enzyme acetylcholinesterase (AChE) by nerve agents (NAs) leads to irreversible inhibition of the enzyme and accumulation of neurotransmitter acetylcholine, which induces cholinergic crisis, that is, overstimulation of muscarinic and nicotinic membrane receptors in the ce...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2020-12-01
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Series: | Arhiv za Higijenu Rada i Toksikologiju |
Subjects: | |
Online Access: | https://doi.org/10.2478/aiht-2020-71-3459 |