Discovering genetic mechanisms underlying the co-occurrence of Parkinson’s disease and non-motor traits

Abstract Understanding the biological mechanisms that underlie the non-motor symptoms of Parkinson’s disease (PD) requires comprehensive frameworks that unravel the complex interplay of genetic risk factors. Here, we used a disease-agnostic brain cortex gene regulatory network integrated with Mendel...

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Bibliographic Details
Main Authors: Sreemol Gokuladhas, Tayaza Fadason, Sophie Farrow, Antony Cooper, Justin M. O’Sullivan
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-024-00638-w