Immunoassays for scarce tumour-antigens in exosomes: detection of the human NKG2D-Ligand, MICA, in tetraspanin-containing nanovesicles from melanoma

Immunoassays for scarce tumour-antigens in exosomes: detection of the human NKG2D-Ligand, MICA, in tetraspanin-containing nanovesicles from melanoma

Abstract Background Tumour-derived exosomes can be released to serum and provide information on the features of the malignancy, however, in order to perform systematic studies in biological samples, faster diagnostic techniques are needed, especially for detection of low abundance proteins. Most hum...

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Bibliographic Details
Main Authors: Sheila López-Cobo, Carmen Campos-Silva, Amanda Moyano, Myriam Oliveira-Rodríguez, Annette Paschen, María Yáñez-Mó, María Carmen Blanco-López, Mar Valés-Gómez
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Journal of Nanobiotechnology
Subjects:
Lateral flow
Immune capture
Exosomes
Tumour antigens
Steric hindrance
Aggregation
Online Access:http://link.springer.com/article/10.1186/s12951-018-0372-z

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http://link.springer.com/article/10.1186/s12951-018-0372-z

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