A scaffold lncRNA shapes the mitosis to meiosis switch

In fission yeast, the antagonistic RNA-binding proteins Mmi1 and Mei2 respectively promote and inhibit meiotic mRNA degradation during mitotic growth. Here the authors show that the lncRNA mamRNA scaffolds Mmi1 and Mei2 proteins to enable their mutual controls.

Bibliographic Details
Main Authors: Vedrana Andric, Alicia Nevers, Ditipriya Hazra, Sylvie Auxilien, Alexandra Menant, Marc Graille, Benoit Palancade, Mathieu Rougemaille
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21032-7