In vivo genetic analysis of Pseudomonas aeruginosa carbon catabolic repression through the study of CrcZ pseudo-revertants shows that Crc-mediated metabolic robustness is needed for proficient bacterial virulence and antibiotic resistance
ABSTRACT Pseudomonas aeruginosa is an opportunistic bacterial pathogen able to colonize a variety of habitats. Its success in colonizing these habitats relies on its metabolic robustness and its capability of efficiently using available carbon sources in a hierarchical way. P. aeruginosa carbon cata...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2023-12-01
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Series: | Microbiology Spectrum |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/spectrum.02350-23 |