Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin
Class III myosins (Myo3) and actin-bundling protein Espin play critical roles in regulating the development and maintenance of stereocilia in vertebrate hair cells, and their defects cause hereditary hearing impairments. Myo3 interacts with Espin1 through its tail homology I motif (THDI), however it...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2016-01-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/12856 |