Novel 2-Amino-1,4-Naphthoquinone Derivatives Induce A549 Cell Death through Autophagy

Novel 2-Amino-1,4-Naphthoquinone Derivatives Induce A549 Cell Death through Autophagy

A series of 1,4-naphthoquinone derivatives containing were synthesized as anti-cancer agents and the crystal structure of compound <b>5a</b> was confirmed by X-ray diffraction. In addition, the inhibitory activities against four cancer cell lines (HepG2, A549, K562, and PC-3) were tested...

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Bibliographic Details
Main Authors: Hua-Yuan Tan, Feng-Ming Liang, Wen-Jing Zhang, Yi Zhang, Jun-Hao Cui, Yu-Yu Dai, Xue-Mei Qiu, Wen-Hang Wang, Yue Zhou, Dan-Ping Chen, Cheng-Peng Li
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Molecules
Subjects:
2-amino-1,4-naphthoquinone
single crystal
autophagy
Online Access:https://www.mdpi.com/1420-3049/28/8/3289

Internet

https://www.mdpi.com/1420-3049/28/8/3289

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