Autophagy-prominent cell clusters among human lens epithelial cells: integrated single-cell RNA-sequencing analysis

Abstract Background Autophagy is an important process that maintains the quality of intracellular proteins and organelles. There is extensive evidence that autophagy has an important role in the lens. Human lens epithelial cells (HLECs) play a key role in the internal homeostasis of the lens. HLEC s...

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Bibliographic Details
Main Authors: Jiasheng Liu, Mengchao Zhu, Yitong Xu, Mengdi Zhang, Haisen Sun, Yaqi Wang, Qingwen Yang, Jin Li
Format: Article
Language:English
Published: BMC 2023-04-01
Series:BMC Ophthalmology
Subjects:
Online Access:https://doi.org/10.1186/s12886-023-02910-8