Emerging Approaches to Investigate the Influence of Transition Metals in the Proteinopathies

Emerging Approaches to Investigate the Influence of Transition Metals in the Proteinopathies

Transition metals have essential roles in brain structure and function, and are associated with pathological processes in neurodegenerative disorders classed as proteinopathies. Synchrotron X-ray techniques, coupled with ultrahigh-resolution mass spectrometry, have been applied to study iron and cop...

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Bibliographic Details
Main Authors: Frederik Lermyte, James Everett, Jake Brooks, Francesca Bellingeri, Kharmen Billimoria, Peter J. Sadler, Peter B. O’Connor, Neil D. Telling, Joanna F. Collingwood
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cells
Subjects:
alzheimer’s disease
parkinson’s disease
amyloid β
α-synuclein
copper
iron
mass spectrometry
electrospray ionization
x-ray
spectromicroscopy
Online Access:https://www.mdpi.com/2073-4409/8/10/1231

Internet

https://www.mdpi.com/2073-4409/8/10/1231

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