CyclinD1 inhibits dicer and crucial miRNA expression by chromatin modification to promote the progression of intrahepatic cholangiocarcinoma

CyclinD1 inhibits dicer and crucial miRNA expression by chromatin modification to promote the progression of intrahepatic cholangiocarcinoma

Abstract Background CyclinD1 is crucial for cell cycling and can regulate the expression of Dicer, a crucial regulator of microRNA maturation. However, little is known on how CyclinD1 regulates Dicer and miRNA expression, and the progression of intrahepatic cholangiocarcinoma (ICC). Methods The expr...

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Bibliographic Details
Main Authors: Yongqiang Qi, Da Wang, Wenhua Huang, Bing Wang, Di Huang, Fei Xiong, Xiaoping Chen, Yongjun Chen
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
CyclinD1
Dicer
Methylation
Cholangiocarcinoma
Online Access:http://link.springer.com/article/10.1186/s13046-019-1415-5

Internet

http://link.springer.com/article/10.1186/s13046-019-1415-5

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