Multiplexed imaging of immune cells in staged multiple sclerosis lesions by mass cytometry

Multiplexed imaging of immune cells in staged multiple sclerosis lesions by mass cytometry

Multiple sclerosis (MS) is characterized by demyelinated and inflammatory lesions in the brain and spinal cord that are highly variable in terms of cellular content. Here, we used imaging mass cytometry (IMC) to enable the simultaneous imaging of 15+ proteins within staged MS lesions. To test the po...

Full description

Bibliographic Details
Main Authors: Valeria Ramaglia, Salma Sheikh-Mohamed, Karen Legg, Calvin Park, Olga L Rojas, Stephanie Zandee, Fred Fu, Olga Ornatsky, Eric C Swanson, David Pitt, Alexandre Prat, Trevor D McKee, Jennifer L Gommerman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-08-01
Series:eLife
Subjects:
imaging mass cytometry
multiple sclerosis
lesions
immunopathology
Online Access:https://elifesciences.org/articles/48051

Internet

https://elifesciences.org/articles/48051

Similar Items