Sterculic Acid: The Mechanisms of Action beyond Stearoyl-CoA Desaturase Inhibition and Therapeutic Opportunities in Human Diseases

In many tissues, stearoyl-CoA desaturase 1 (SCD1) catalyzes the biosynthesis of monounsaturated fatty acids (MUFAS), (i.e., palmitoleate and oleate) from their saturated fatty acid (SFA) precursors (i.e., palmitate and stearate), influencing cellular membrane physiology and signaling, leading to bro...

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Bibliographic Details
Main Authors: Rafael Peláez, Ana Pariente, Álvaro Pérez-Sala, Ignacio M. Larráyoz
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/1/140