The Mycobacterium avium ssp. paratuberculosis specific mptD gene is required for maintaining of the metabolic homeostasis necessary for full virulence in mouse infections

The Mycobacterium avium ssp. paratuberculosis specific mptD gene is required for maintaining of the metabolic homeostasis necessary for full virulence in mouse infections

Mycobacterium avium subspecies paratuberculosis (MAP) causes Johne's disease, a chronic granulomatous enteritis in ruminants. Furthermore, infections of humans with MAP have been reported and a possible association with Crohn's disease and diabetes type I is currently discussed. MAP owns l...

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Bibliographic Details
Main Authors: Thorsten eMeißner, Elke eEckelt, Tina eBasler, Jochen eMeens, Julia eHeinzmann, Aabdulhadi eSuwandi, Walter Martin Roland Oelemann, Sandra eTrenkamp, Otto eHolst, Siegfried eWeiss, Boyke eBunk, Cathrin eSpöer, Gerald-F. eGerlach, Ralph eGoethe
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Lipids
Macrophages
Metabolism
Mycobacterium Infections
Survival
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00110/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00110/full

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