Co-Detection of VEGF-A and Its Regulator, microRNA-181a, May Indicate Central Nervous System Involvement in Pediatric Leukemia

Central nervous system (CNS) involvement is a leading cause of therapy-refractory pediatric acute lymphoblastic leukemia (pALL), which is aggravated by underdiagnosing CNS disease with the currently used cell-based approach of cerebrospinal fluid (CSF) diagnostics. Our study focused on developing no...

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Bibliographic Details
Main Authors: Bálint Egyed, Anna Horváth, Ágnes F. Semsei, Csaba Szalai, Judit Müller, Dániel J. Erdélyi, Gábor T. Kovács
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Pathology and Oncology Research
Subjects:
Online Access:https://www.por-journal.com/articles/10.3389/pore.2022.1610096/full