Artemisinin Mediates Its Tumor-Suppressive Activity in Hepatocellular Carcinoma Through Targeted Inhibition of FoxM1

Artemisinin Mediates Its Tumor-Suppressive Activity in Hepatocellular Carcinoma Through Targeted Inhibition of FoxM1

The aberrant up-regulation of the oncogenic transcription factor Forkhead box M1 (FoxM1) is associated with tumor development, progression and metastasis in a myriad of carcinomas, thus establishing it as an attractive target for anticancer drug development. FoxM1 overexpression in hepatocellular ca...

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Bibliographic Details
Main Authors: Deeptashree Nandi, Pradeep Singh Cheema, Aakriti Singal, Hina Bharti, Alo Nag
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Oncology
Subjects:
artemisinin (ART)
FOXM1 (Forkhead box M1)
hepatocellular carcinoma (HCC)
anticancer
anticarcinogenic agent
drug resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.751271/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.751271/full

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