Myeloid zinc finger 1 (Mzf1) differentially modulates murine cardiogenesis by interacting with an Nkx2.5 cardiac enhancer.

Vertebrate heart development is strictly regulated by temporal and spatial expression of growth and transcription factors (TFs). We analyzed nine TFs, selected by in silico analysis of an Nkx2.5 enhancer, for their ability to transactivate the respective enhancer element that drives, specifically, e...

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Main Authors: Stefanie A Doppler, Astrid Werner, Melanie Barz, Harald Lahm, Marcus-André Deutsch, Martina Dreßen, Matthias Schiemann, Bernhard Voss, Serge Gregoire, Rajarajan Kuppusamy, Sean M Wu, Rüdiger Lange, Markus Krane
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0113775&type=printable