Inhibitory effects of flavonoids isolated from Sophora flavescens on indoleamine 2,3-dioxygenase 1 activity

Inhibitory effects of flavonoids isolated from Sophora flavescens on indoleamine 2,3-dioxygenase 1 activity

Indoleamine 2,3-dioxygenase 1 (IDO1), a tryptophan catabolising enzyme, is known as a tumour cell survival factor that causes immune escape in several types of cancer. Flavonoids of Sophora flavescens have a variety of biological benefits for humans; however, cancer immunotherapy effect has not been...

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Bibliographic Details
Main Authors: Mincheol Kwon, Sung-Kyun Ko, Mina Jang, Gun-Hee Kim, In-Ja Ryoo, Sangkeun Son, Hyung Won Ryu, Sei-Ryang Oh, Won-Kyu Lee, Bo Yeon Kim, Jae-Hyuk Jang, Jong Seog Ahn
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
indoleamine 2,3-dioxygenase 1 (ido1)
ido1 inhibitor
sophora flavescens
flavonoid
Online Access:http://dx.doi.org/10.1080/14756366.2019.1640218

Internet

http://dx.doi.org/10.1080/14756366.2019.1640218

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