Multiple Sclerosis-Associated Changes in the Composition and Immune Functions of Spore-Forming Bacteria

Multiple Sclerosis-Associated Changes in the Composition and Immune Functions of Spore-Forming Bacteria

ABSTRACT Multiple sclerosis (MS) is an autoimmune disease of the central nervous system characterized by adaptive and innate immune system dysregulation. Recent work has revealed moderate alteration of gut microbial communities in subjects with MS and in experimental, induced models. However, a mech...

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Bibliographic Details
Main Authors: Egle Cekanaviciute, Anne-Katrin Pröbstel, Anna Thomann, Tessel F. Runia, Patrizia Casaccia, Ilana Katz Sand, Elizabeth Crabtree, Sneha Singh, John Morrissey, Patrick Barba, Refujia Gomez, Rob Knight, Sarkis Mazmanian, Jennifer Graves, Bruce A. C. Cree, Scott S. Zamvil, Sergio E. Baranzini
Format: Article
Language:English
Published: American Society for Microbiology 2018-10-01
Series:mSystems
Subjects:
immune mechanisms
multiple sclerosis
spore-forming bacteria
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00083-18

Internet

https://journals.asm.org/doi/10.1128/mSystems.00083-18

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