The Cholinergic Pathway and MitoKATP Induce UCP4 Expression Involved in Neuroprotection of FN Stimulation in Rats

The Cholinergic Pathway and MitoKATP Induce UCP4 Expression Involved in Neuroprotection of FN Stimulation in Rats

Background Electrical stimulation of the cerebellar fastigial nucleus (FN) reduces the infarct size induced by middle cerebral artery occlusion in rats. FN stimulation confers long‐lasting protection from brain injury; however, its underlying mechanism is not yet understood. We aimed to elucidate th...

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Bibliographic Details
Main Authors: Yasuko Fukushi, Eugene V. Golanov, Shinichiro Koizumi, Min Thura, Hayato Ihara, Seiji Yamamoto
Format: Article
Language:English
Published: Wiley 2022-11-01
Series:Stroke: Vascular and Interventional Neurology
Subjects:
brain injury
ischemic tolerance
middle cerebral artery occlusion
reactive oxygen species
uncoupling protein
Online Access:https://www.ahajournals.org/doi/10.1161/SVIN.122.000362

Internet

https://www.ahajournals.org/doi/10.1161/SVIN.122.000362

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