Gut-derived lipopolysaccharide promotes alcoholic hepatosteatosis and subsequent hepatocellular carcinoma by stimulating neutrophil extracellular traps through toll-like receptor 4

Gut-derived lipopolysaccharide promotes alcoholic hepatosteatosis and subsequent hepatocellular carcinoma by stimulating neutrophil extracellular traps through toll-like receptor 4

Background/Aims Binge drinking leads to many disorders, including alcoholic hepatosteatosis, which is characterized by intrahepatic neutrophil infiltration and increases the risk of hepatocellular carcinoma (HCC). Molecular mechanisms may involve the migration of bacterial metabolites from the gut t...

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Bibliographic Details
Main Authors: Yang Liu, Xin Zhang, Shuo Chen, Jiazhong Wang, Shuo Yu, Yiming Li, Meng Xu, Harouna Aboubacar, Junhui Li, Tao Shan, Jixin Wang, Gang Cao
Format: Article
Language:English
Published: Korean Association for the Study of the Liver 2022-07-01
Series:Clinical and Molecular Hepatology
Subjects:
extracellular traps
alcoholics
hepatosteatosis
hepatocellular carcinoma
lipopolysaccharides
toll-like receptor 4
Online Access:http://e-cmh.org/upload/pdf/cmh-2022-0039.pdf

Internet

http://e-cmh.org/upload/pdf/cmh-2022-0039.pdf

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