Viral and immunologic evaluation of smokers with severe COVID-19

Abstract Smoking negatively affects B cell function and immunoglobulin levels, but it is unclear if this immune dysfunction contributes to the risk of severe COVID-19 in smokers. We evaluated binding IgM, IgA and IgG antibodies to spike and receptor binding domain antigens, and used a pseudovirus as...

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Bibliographic Details
Main Authors: Joseph Vecchio, James Regan, Yuting Jiang, Roy Li, Hannah Romain, Fizah Yousuf, Thomas Adel, Kevin Hall, Jeffrey M. DaCosta, Xu Yu, Jonathan Z. Li, Ismael Ben Fofana
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-45195-z