Nanostructured Lipid Carriers Can Enhance Oral Absorption of Khellin, a Natural Pleiotropic Molecule

Nanostructured Lipid Carriers Can Enhance Oral Absorption of Khellin, a Natural Pleiotropic Molecule

A novel formulation based on nanostructured lipid carriers (NLCs) was developed to increase solubility and intestinal absorption of khellin. K-NLCs were prepared with stearic acid, hempseed oil, Brij S20, and Labrafil M 1944 CS, using the emulsification-ultrasonication method. Developed nanoparticle...

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Bibliographic Details
Main Authors: Giulia Vanti, Lucrezia Muti, Mario D’Ambrosio, Lucia Grifoni, Maria Camilla Bergonzi, Cristina Luceri, Anna Rita Bilia
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Molecules
Subjects:
khellin
nanostructured lipid carriers
oral administration
lyophilization
release study
gastrointestinal stability
Online Access:https://www.mdpi.com/1420-3049/26/24/7657

Internet

https://www.mdpi.com/1420-3049/26/24/7657

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