Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein

Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein

<p/> <p>Background</p> <p>Evidence from biochemical, epidemiological and genetic findings indicates that cholesterol levels are linked to amyloid-β (Aβ) production and Alzheimer's disease (AD). Oxysterols, which are cholesterol-derived ligands of the liver X receptors (L...

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Bibliographic Details
Main Authors: Seabrook Guy R, Ray William J, Suon Sokreine, Guillily Maria, Chen Ci-Di, Cordy Joanna M, Zerbinatti Celina V, Abraham Carmela R, Wolozin Benjamin
Format: Article
Language:English
Published: BMC 2008-03-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/3/1/5

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http://www.molecularneurodegeneration.com/content/3/1/5

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