eSVD-DE: cohort-wide differential expression in single-cell RNA-seq data using exponential-family embeddings
Abstract Background Single-cell RNA-sequencing (scRNA) datasets are becoming increasingly popular in clinical and cohort studies, but there is a lack of methods to investigate differentially expressed (DE) genes among such datasets with numerous individuals. While numerous methods exist to find DE g...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-03-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-024-05724-7 |