Is real time PCR preferable to the direct immunofluorescence in the diagnosis of Pneumocystis jirovecii pneumonia in HIV-infected patients?

Is real time PCR preferable to the direct immunofluorescence in the diagnosis of Pneumocystis jirovecii pneumonia in HIV-infected patients?

Abstract Objectives In this study, we compared IFA and real-time PCR in bronchoalveolar lavage specimens of HIV infected patients. A total of 66 BALs from 62 HIV patients were included in the study. 30 IFA positive and 36 IFA negative specimens were tested with real-time PCR, targeting the major sur...

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Bibliographic Details
Main Authors: Simon Bossart, Konrad Mühlethaler, Christian Garzoni, Hansjakob Furrer
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Research Notes
Subjects:
HIV
Pneumocystis jirovecii
Pneumocystis pneumonia
Immunofluorescence assay
Real-time PCR
Online Access:http://link.springer.com/article/10.1186/s13104-020-05075-5

Internet

http://link.springer.com/article/10.1186/s13104-020-05075-5

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