N-acetylcysteine dose-dependently improves the analgesic effect of acetaminophen on the rat hot plate test
Abstract Background Acetaminophen (APAP) induced hepatotoxicity is a clinically important problem. Up to now, interventive therapy with n-acetylcysteine (NAC) has been considered as a gold-standard treatment for APAP overdose. However, no study has focused on the efficacy of these drugs’ concurrent...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-01-01
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Series: | BMC Pharmacology and Toxicology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40360-020-00469-4 |