Transcription Factors and ncRNAs Associated with <i>CYP3A</i> Expression in Human Liver and Small Intestine Assessed with Weighted Gene Co-Expression Network Analysis

Transcription Factors and ncRNAs Associated with <i>CYP3A</i> Expression in Human Liver and Small Intestine Assessed with Weighted Gene Co-Expression Network Analysis

CYP3A4, CYP3A5, and CYP3A7, which are located in a multigene locus (<i>CYP3A</i>), play crucial roles in drug metabolism. To understand the highly variable hepatic expression of CYP3As, regulatory network analyses have focused on transcription factors (TFs). Since long non-coding RNAs (l...

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Bibliographic Details
Main Authors: Huina Huang, Siqi Zhang, Xiaozhen Wen, Wolfgang Sadee, Danxin Wang, Siyao Yang, Liang Li
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biomedicines
Subjects:
cytochrome P450
WGCNA
transcription factor
long non-coding RNA
regulatory network
Online Access:https://www.mdpi.com/2227-9059/10/12/3061

Internet

https://www.mdpi.com/2227-9059/10/12/3061

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