Neurodevelopmental disruption of cortico-striatal function caused by degeneration of habenula neurons.

The habenula plays an important role on cognitive and affective functions by regulating monoamines transmission such as the dopamine and serotonin, such that its dysfunction is thought to underlie a number of psychiatric conditions. Given that the monoamine systems are highly vulnerable to neurodeve...

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Bibliographic Details
Main Authors: Young-A Lee, Yukiori Goto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3084869?pdf=render