Causal relationship between hypothyroidism and coronary atherosclerotic cardiovascular disease: a bidirectional two-sample Mendelian randomization

Causal relationship between hypothyroidism and coronary atherosclerotic cardiovascular disease: a bidirectional two-sample Mendelian randomization

BackgroundEpidemiological and observational studies demonstrate a comorbid relationship between hypothyroidism and atherosclerotic cardiovascular disease (ASCVD). The nature and direction of this causal relationship, however, remain unclear.ObjectiveThis study aims to elucidate the causal relationsh...

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Bibliographic Details
Main Authors: Jiarui Li, Yihan Wang, Xiaoting Luo, Tianwei Meng, Chengjia Li, Juan Li, Likun Du
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
hypothyroidism
atherosclerotic cardiovascular disease
Mendelian randomization
enrichment analysis
causal relationship
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2024.1402359/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2024.1402359/full

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