Long-term viable chimeric nephrons generated from progenitor cells are a reliable model in cisplatin-induced toxicity

Long-term viable chimeric nephrons generated from progenitor cells are a reliable model in cisplatin-induced toxicity

Abstract Kidney organoids have shown promise as evaluation tools, but their in vitro maturity remains limited. Transplantation into adult mice has aided in maturation; however, their lack of urinary tract connection limits long-term viability. Thus, long-term viable generated nephrons have not been...

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Bibliographic Details
Main Authors: Kenji Matsui, Shuichiro Yamanaka, Sandy Chen, Naoto Matsumoto, Keita Morimoto, Yoshitaka Kinoshita, Yuka Inage, Yatsumu Saito, Tsuyoshi Takamura, Toshinari Fujimoto, Susumu Tajiri, Kei Matsumoto, Eiji Kobayashi, Takashi Yokoo
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05484-9

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https://doi.org/10.1038/s42003-023-05484-9

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