Long-term viable chimeric nephrons generated from progenitor cells are a reliable model in cisplatin-induced toxicity
Abstract Kidney organoids have shown promise as evaluation tools, but their in vitro maturity remains limited. Transplantation into adult mice has aided in maturation; however, their lack of urinary tract connection limits long-term viability. Thus, long-term viable generated nephrons have not been...
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-10-01
|
| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-023-05484-9 |