Multivariate Optimization of Chromatographic Conditions for Rapid Simultaneous Quantification of Antidiarrheal Drugs in Formulation Using Surface Response Methodology

Multivariate Optimization of Chromatographic Conditions for Rapid Simultaneous Quantification of Antidiarrheal Drugs in Formulation Using Surface Response Methodology

A combination of antibiotics and antiprotozoal and antisecretory medicines has been prescribed for the treatment of diarrhea. A rapid, reproducible liquid chromatographic procedure was established for the concurrent analysis of metronidazole (MET), ofloxacin (OFL), and racecadotril (RAC) in suspensi...

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Bibliographic Details
Main Authors: Mahesh Attimarad, Katharigatta Narayanaswamy Venugopala, Muhammad S. Chohan, Pottathil Shinu, Marysheela David, Effren II Plaza Molina, Anroop Balachandran Nair, Nagaraja Sreeharsha, Abdulrahman Ibrahim Altaysan, Abdulmalek Ahmed Balgoname
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Separations
Subjects:
HPLC
surface response
multivariate optimization
formulation
metronidazole
ofloxacin
Online Access:https://www.mdpi.com/2297-8739/9/5/103

Internet

https://www.mdpi.com/2297-8739/9/5/103

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