Role of IL-4 in bone marrow driven dysregulated angiogenesis and age-related macular degeneration

Role of IL-4 in bone marrow driven dysregulated angiogenesis and age-related macular degeneration

Age-associated sterile inflammation can cause dysregulated choroidal neovascularization (CNV) as age-related macular degeneration (AMD). Intraocular fluid screening of 234 AMD patients identified high levels of IL-4. The purpose of this study was to determine the functional role of IL-4 in CNV forma...

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Bibliographic Details
Main Authors: Takashi Baba, Dai Miyazaki, Kodai Inata, Ryu Uotani, Hitomi Miyake, Shin-ichi Sasaki, Yumiko Shimizu, Yoshitsugu Inoue, Kazuomi Nakamura
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-05-01
Series:eLife
Subjects:
age-related macular degeneration
choroidal neovascularization
IL-4
angiogenesis
Online Access:https://elifesciences.org/articles/54257

Internet

https://elifesciences.org/articles/54257

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