Prediction formulas for individual opioid analgesic requirements based on genetic polymorphism analyses.

BACKGROUND:The analgesic efficacy of opioids is well known to vary widely among individuals, and various factors related to individual differences in opioid sensitivity have been identified. However, a prediction model to calculate appropriate opioid analgesic requirements has not yet been establish...

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Bibliographic Details
Main Authors: Kaori Yoshida, Daisuke Nishizawa, Takashi Ichinomiya, Tatsuya Ichinohe, Masakazu Hayashida, Ken-ichi Fukuda, Kazutaka Ikeda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4304713?pdf=render