Poor semen parameters are associated with abnormal methylation of imprinted genes in sperm DNA

Abstract Background Altered sperm DNA methylation patterns of imprinted genes as well as certain spermatogenesis-related genes has been proposed as a possible mechanism of male subfertility. Some reports suggest that there is an elevated risk of congenital diseases, associated with imprinted genes,...

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Bibliographic Details
Main Authors: Bing Song, Yujie Chen, Chao Wang, Guanjian Li, Zhaolian Wei, Xiaojin He, Yunxia Cao
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Reproductive Biology and Endocrinology
Subjects:
Online Access:https://doi.org/10.1186/s12958-022-01028-8