Synthesis of Sterically Shielded Nitroxides Using the Reaction of Nitrones with Alkynylmagnesium Bromides

Sterically shielded nitroxides, which demonstrate high resistance to bioreduction, are the spin labels of choice for structural studies inside living cells using pulsed EPR and functional MRI and EPRI in vivo. To prepare new sterically shielded nitroxides, a reaction of cyclic nitrones, including va...

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Bibliographic Details
Main Authors: Sergey A. Dobrynin, Mark M. Gulman, Denis A. Morozov, Irina F. Zhurko, Andrey I. Taratayko, Yulia S. Sotnikova, Yurii I. Glazachev, Yuri V. Gatilov, Igor A. Kirilyuk
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/21/7626